My rule:
1. The moment your floating profit hits a number that makes you think “I’d be perfectly happy if the trade ended right here” → immediately close 50–70 % of the position (whatever size removes the stress).
2. Move the stop-loss on the remaining 30–50 % to breakeven +0.5–1 % (now it can literally only go up from here).
3. Forget the trade exists for the next 24–72 hours. The runner can now hit the TP1 or TP2, or go –60 %, or whatever — it’s 100 % free money.