$BIO surged 59.5% within 24 hours, far exceeding the overall cryptocurrency market's +4.2% increase. The main driving factors include:

1. Clinical trial funding catalyst - approved $80,000 for the Percepta Phase II clinical trial, linking BIO to biotechnology royalties.

2. Staking surge - Staked BIO reached 125 million tokens (3.5% of total supply), tightening liquidity.

3. Technical breakthrough - Price broke through key resistance levels, showing bullish momentum.

4. Listed on Coinbase on July 31, enhancing liquidity.