I used to think Bitcoin and DeFi would never fully fit together. Bitcoin was always the serious, heavyweight asset you kept safe, and DeFi was the wild arena where you experimented with everything except BTC. If I wanted to earn yield or try strategies, I’d move stablecoins or other tokens. Whenever I touched Bitcoin on-chain, it felt like I was forcing it into systems that weren’t really designed for it. Wrapped versions, shady bridges, random farms—it all felt temporary and fragile. That’s why Lorenzo caught my attention in a different way. It doesn’t treat Bitcoin like a guest in DeFi. It behaves like it wants to make BTC a native asset across multichain DeFi, with proper structure, liquidity and tools that actually respect what Bitcoin is.
The first shift for me was understanding that Lorenzo doesn’t see Bitcoin as “just another collateral type.” It brands itself as a Bitcoin liquidity layer, which means BTC is the starting point, not an afterthought. Instead of building a generic DeFi protocol and adding BTC later, Lorenzo starts with Bitcoin and builds a whole stack around it: wrapped representations, staking receipts, yield-bearing tokens, and then structured strategies on top. That approach matters. A lot of protocols can plug BTC in; very few are built around it. If you want BTC to feel native in DeFi, it needs its own infrastructure, not just a seat at someone else’s table.
Multichain is where this becomes really obvious. Bitcoin lives on its own chain, but DeFi lives everywhere—EVM chains, Move chains, app-chains, L2s. In the old model, each chain had its own random BTC wrapper with its own risks and tiny liquidity. It was messy. If I moved my BTC to one ecosystem, it felt like I was locking it away from the rest of the world. Lorenzo’s design tackles exactly that pain. It mints its BTC primitives on a secure base and then pushes them out to multiple ecosystems as standard representations—so the same underlying BTC liquidity can move through different chains without losing its identity every time. That’s the difference between being “bridged in” and being “truly present” across ecosystems.
The reason this feels like native status to me is the way Lorenzo plugs into each chain’s core DeFi pieces instead of just sitting as a token on a list. On Sui and the Move ecosystem, for example, stBTC isn’t just a wrapped coin; it’s inside the main DEX liquidity pools, the main lending markets, and the main yield loops. That means Bitcoin, through stBTC, is part of the trading routes, part of the collateral framework and part of the day-to-day liquidity flows. When a token lives in DEX pairs, lending protocols and structured products, it stops being “visiting liquidity” and starts being part of the ecosystem’s bloodstream. That’s what native looks like in DeFi: you’re not on the sidelines; you’re in the routing logic.
For me as a user, this changes how I think about where my BTC can live. Earlier, if I wanted to use Bitcoin in DeFi, I always felt like I was compromising. I had to pick one chain, one wrapper, one set of risks, and then hope nothing went wrong. Now, with Lorenzo’s multichain approach, I can treat Bitcoin more like a global asset with local utilities. I can have BTC represented as stBTC or enzoBTC moving into different chains, strategies and protocols, but it all still feels connected. It’s not ten different random tokens; it’s one liquidity system stretched across multiple environments. That mental shift from “fragmented BTC” to “networked BTC” is a big part of why it feels truly native.
Another thing Lorenzo gets right, in my opinion, is the balance between yield and identity. A lot of “BTC in DeFi” attempts pushed Bitcoin into hyper-volatile pools or reckless farms just to advertise big APYs. It always felt off: the most conservative, long-term asset in the space being treated like a lottery ticket. Lorenzo’s approach is quieter and more aligned with how serious BTC holders actually think. It wraps BTC into structured yield paths—staking receipts, tokenized funds, multi-strategy vaults—so the yield comes from diversified, more defensible sources. That doesn’t remove risk, but it changes the tone completely. It’s not “throw Bitcoin into a degen pit and pray.” It’s “route Bitcoin through a portfolio engine designed to make it productive while still respecting that this is BTC.”
Multichain DeFi also needs something else: standards. Without standards, everything becomes a mess of incompatible wrappers and tiny pools. Lorenzo’s BTC stack looks like an attempt to define those standards from a Bitcoin-first angle. enzoBTC as the wrapped base, stBTC as the staked representation, and higher-level yield-bearing tokens as strategy outputs. Once those become widely recognised, other protocols don’t have to reinvent Bitcoin every time—they can just plug into these objects and treat them like native building blocks. That’s how ERC-20 and stablecoins became “ordinary” in DeFi. Lorenzo is trying to do something similar for BTC across chains, and that’s exactly what you’d expect from a protocol aiming to be the Bitcoin liquidity backbone.
From a psychological angle, I also notice that using Lorenzo changes how comfortable I feel about moving BTC around DeFi. I still respect the risk, but it doesn’t feel like a weird, one-off experiment anymore. It feels like routing funds through a system whose whole reason for existing is to handle Bitcoin intelligently. This is important because multichain DeFi is noisy and confusing. Bridges, L2s, new chains, new narratives—everything is always changing. Having one stable logic for BTC across that chaos, via Lorenzo’s layer, gives me a sense of continuity. My Bitcoin doesn’t get lost culturally every time it enters a new ecosystem; it just puts on a different interface where needed while staying part of the same underlying network.
I also think about what this means for builders and protocols themselves. Most teams that want BTC liquidity don’t want to become Bitcoin infrastructure experts; they just want a clean, reliable way to bring BTC into their DEX, lending market, options platform or app. Lorenzo gives them that: instead of managing bridges, wrappers and yield routing themselves, they can integrate enzoBTC, stBTC and related tokens and instantly tap into a broader BTC liquidity layer. That’s when Bitcoin stops being “special case” code and becomes standard integration. From the outside, users just see that their favourite protocol supports BTC properly; under the hood, Lorenzo is doing the heavy lifting.
For the broader crypto landscape, this direction feels inevitable. Bitcoin is still the dominant asset in terms of value and mindshare. If DeFi wants to claim it’s building real financial infrastructure, it can’t keep treating BTC as something that gets parked in cold storage and occasionally wrapped into random experiments. It has to make Bitcoin a first-class, routable, composable, yield-bearing asset across chains. Lorenzo is one of the first systems I’ve seen that actually behaves like it understands that responsibility. It isn’t trying to own every use case; it’s trying to own the BTC pipes that feed them.
In the end, saying “Lorenzo is quietly making Bitcoin a native asset in multichain DeFi” is my way of describing a shift I can actually feel when I use it. Before, touching BTC in DeFi felt like a special event. Now, because of the structure Lorenzo provides, it feels normal. I can stake, wrap, move, lend and use Bitcoin across ecosystems without constantly feeling like I’m breaking it out of its natural environment. That’s what “native” really means here—not that Bitcoin left its original chain forever, but that it finally has infrastructure elsewhere that treats it like it belongs. And the more this layer grows, the more I expect people to stop asking “Can BTC work in DeFi?” and start asking a different question: “Which Bitcoin liquidity layer are you using?”
For me, that answer is increasingly simple. The one that was actually designed for Bitcoin from day one. The one that respects its role, its risks and its potential across chains. The one that doesn’t shout the loudest, but quietly connects more and more of the multichain map together. Right now, that layer is Lorenzo.


